GERMLINE MUTATION IN NLRP2 (NALP2) IN A FAMILIAL IMPRINTING DISORDER (BECKWITH-WIEDEMANN SYNDROME).


Insect resistance responses of ten Aster varieties to damage by Tephritis angustipennis in the three rivers source region of China

Abstract Aster varieties are widely used for medicinal purposes, landscaping, and ecological restoration, but their growth and reproduction are significantly threatened by the seed predator Tephritis angustipennis (Diptera: Tephritidae).The cultivation of pest-resistant varieties offers an effective, economical, and eco-friendly approach to managin

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Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector

ABSTRACT Intramuscular vaccination of mice with the naked pBI-11 DNA plasmid targeting E6 and E7 of HPV16 and HPV18 via a conventional syringe and needle generates human papillomavirus (HPV) antigen-specific CD8+ T cell-mediated immune responses and therapeutic effects against the TC-1 tumor model.However, delivery of DNA vaccines by this method is

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